The midbrain receives its blood supply from the paramedian mesencephalic branches (basilar), peduncular perforating branches (posterior cerebral artery) as well as from the superior cerebellar artery, and the choroidal arteries. A lesion in the ventromedial portion of midbrain leads to weber syndrome. Weber's syndrome refers to alternating syndromes, the essence of which is the functional breakdown of the cranial nerves on the part of the lesion, as well as in the disturbance of motor activity (in the form of paresis and paralysis), loss of sensitivity (conductor variant), and coordination of movements.
OslerWeberRendu Disease. Multiple, punctuate, red mac
The classical presentation relates to the brain lesion (cerebral angiomatous lesion of leptomeninges, which is responsible for epileptic seizures, hemiparesis and mental retardation), skin lesion (unilateral facial nevus), ocular and oral involvement.
Weber syndrome is characterized by oculomotor palsy and contralateral hemiparesis.
Prenatal diagnosis using ultrasound has been reported. The prevalence of ktws is 1 : We highly recommend watching our midbrain anatomy & function lecture. The exact pathophysiology and genetic etiology of the disorder are unknown.
Typical clinical findings include ipsilateral cn.
[ 10] weber syndrome secondary to brain stem tuberculoma. The midbrain receives its blood supply from the paramedian mesencephalic branches (basilar), peduncular perforating branches (posterior cerebral artery) as well as from the superior cerebellar artery, and the choroidal arteries. Occasionally the substantia nigra can also be involved 5. Weber's syndrome, also known as midbrain stroke syndrome or superior alternating hemiplegia, is a form of stroke that affects the medial portion of the midbrain.
Weber syndrome, classically described as a midbrain stroke syndrome and superior alternating hemiplegia,.
Weber syndrome occurs with an occlusion of the median and/or paramedian perforating branches of the basilar artery. It involves oculomotor fascicles in the interpeduncular cisterns and cerebral peduncle so it characterizes the presence of an ipsilateral lower motor neuron type oculomotor nerve palsy. Ipsilateral oculomotor nerve palsy with contralateral hemiparesis or hemiplegia. In this lecture professor zach murphy will present on the four most common midbrain lesions including benedikt, weber, claude, and parinaud syndrome.
Any midbrain lesion causing a combination of ipsilateral third nerve palsy and contralateral hemiplegia is known as weber syndrome which was first described and named after weber.
Branches of posterior cereebral artery (pca) and top of basilar artery. Weber syndrome affects what nerve. [ 9] it is commonly caused by vascular pathology such as an infarction or aneurysm, tumor, and demyelination. A lesion in the ventromedial portion of midbrain leads to weber syndrome.
Claude syndrome shows oculomotor palsy and contralateral ataxia.
Clinical presentation ipsilateral cn iii pa.
